Conoidin A

Product Details
Formula	C10H8Br2N2O2
Molecular Weight	347.99
Appearance	Solid
Purity	98.03%
Smiles String	[O-][N+]1=C(C(CBr)=[N+](C2=C1C=CC=C2)[O-])CBr

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 µM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII). Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease.

! For research use only. Not intended for any clinical use.