CMF019

Cat. No: CDIA-0598

CAS. No.: 1586787-08-7

Size: 5 mg

Price: Inquiry

Product Details
Formula	C25H33N3O3S
Molecular Weight	455.61
Appearance	Solid
Purity	99.05%
Smiles String	CC(C)C[[email protected]](NC(C1=CC=C2C(N=C(CC3=CC=CS3)N2C(CC)CC)=C1)=O)CC(O)=O

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Description

CMF019 is a potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin.

! For research use only. Not intended for any clinical use.