CCG258208

Cat. No: CDIA-1282

CAS. No.: 2055990-90-2

Synonyms: GRKs-IN-1

Size: 50 mg

Price: Inquiry

Product Details
Formula	C24H25FN4O4
Molecular Weight	452.48
Smiles String	FC1=C(C(NCC2=NNC=C2)=O)C=C([[email protected]]3[[email protected]](COC4=CC=C(OCO5)C5=C4)CNCC3)C=C1

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

Description

CCG258208 (GRK2-IN-1) is a potent and selective GRK2 (G protein-coupled receptor kinase 2) inhibitor (IC50=30 nM) while maintaining 230-fold selectivity over GRK5 (IC50=7.09 μM) and more than 2500-fold selectivity over GRK1 (IC50=87.3 μM), PKA, and ROCK1. CCG258208 can be used in heart failure research.

! For research use only. Not intended for any clinical use.