BQ-123 TFA

Cat. No: CDIA-1358

Size: 50 mg

Price: Inquiry

Product Details
Formula	C33H43F3N6O9
Molecular Weight	724.72
Smiles String	O=C(N[[email protected]](C(N(CCC1)[[email protected]]1([H])C2=O)=O)([H])CC(O)=O)[[email protected]](NC([[email protected]@H](NC([[email protected]](N2)C(C)C)=O)CC(C)C)=O)CC3=CNC4=CC=CC=C34.OC(C(F)(F)F)=O

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

Description

BQ-123 TFA is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM and a Ki of 25 nM. BQ-123 TFA inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension.

! For research use only. Not intended for any clinical use.