BMS-309403
Cat. No: CDIA-0055
CAS. No.: 300657-03-8
Size: 1 mg
| Product Details |
| Formula |
C31H26N2O3 |
| Molecular Weight |
474.55 |
| Appearance |
Solid |
| Purity |
99.87% |
| Smiles String |
O=C(O)COC1=CC(C2=CC=CC=C2N3N=C(C4=CC=CC=C4)C(C5=CC=CC=C5)=C3CC)=CC=C1 |
| Storage & Handling |
| Shipping |
Room temperature. |
| Storage Powder |
-20 °C/3 years, 4 °C/2 years |
Description
BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells.
! For research use only. Not intended for any clinical use.
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