Biostability Evaluation Services for Cardiovascular Implant Materials

Since cardiovascular implants usually are intended for long-term use, the biostability of cardiovascular implant materials is an important factor in determining the quality of cardiovascular implants. Ace Therapeutics can provide biostability evaluation services for implant materials to advance the development of cardiovascular implants.

Overview of Biostability of Implant Materials

For artificial implants implanted in the body, it is important for implant materials to have good biostability with human tissues and body fluids to meet the requirements of long-term use. Over the past decades, many materials, including polymers and metallic materials, have been widely used in the manufacture of implants. For example, silicone rubber is promising for medical use because it is physiologically inert, does not age easily, and does not cause blood clotting.

Fig. 1 Rabbit biostability study sample construction and subcutaneous implant locations. (Jenney C, et al., 2021)

Ace Therapeutics strives to provide high-quality biostability evaluation services for implant materials to advance your research of cardiovascular implants. 

In Vitro Enzyme Stability Testing

We provide enzyme stability evaluation services for cardiovascular implant materials under in vitro conditions to test the stability of implant materials against common enzymes, such as papain, trypsin, and esterase.

In Vitro Accelerated Stability Testing

We provide accelerated stability services for cardiovascular implant materials. We simulate the aging of implant materials by storing samples at high temperatures for a period of time to provide stability data for cardiovascular implant materials.

In Vivo Implant Stability Testing

We can provide implantation studies in experiment animals to obtain in vivo stability data for cardiovascular implant materials.

Ace Therapeutics has extensive research experience in the development for cardiovascular implants. We are committed to providing biostability evaluation services for cardiovascular implant materials to assist our clients in advancing their research. If you are interested in our services for cardiovascular implant materials, please do not hesitate to contact us.

1. Jenney, C., et al. Assessment of a siloxane poly (urethane‐urea) elastomer designed for implantable heart valve leaflets. Advanced NanoBiomed Research, 2021, 1(2): 2000032.