BI-749327

Cat. No: CDIA-0172

CAS. No.: 2361241-23-6

Size: 1 mg

Price: Inquiry

Product Details
Formula	C23H21F3N4O2
Molecular Weight	442.43
Appearance	Solid
Purity	98.49%
Smiles String	NC1=NN=C(C2CCN(C(C3=CC=C(OC4=CC=C(C(F)(F)F)C=C4)C=C3)=O)CC2)C=C1

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Description

BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold versus TRPC7.

! For research use only. Not intended for any clinical use.