AV123
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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

AV123

Cat. No: CDIA-1981
CAS. No.: 233605-81-7
Size: 500 μg
Price: Inquiry
Product Details
Formula C11H14N4O2
Molecular Weight 234.25
Smiles String O=[N+](C1=CC=C2C(NC(NCCCC)=N2)=C1)[O-]
Storage & Handling
Shipping Room temperature.
Storage Please refer to the instruction manual.

Description

AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor (IC50=12.12 µM). AV123 blocks the TNF-α-induced necroptotic (EC50=1.7 μM) but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases.

! For research use only. Not intended for any clinical use.