APJ receptor agonist 5

Cat. No: CDIA-1912

CAS. No.: 2135514-20-2

Size: 50 mg

Price: Inquiry

Product Details
Formula	C26H29N3O6
Molecular Weight	479.52
Smiles String	CCOCC(N(C1=C(C=CC=C1OC)OC)C(O)=C2C(N3C[[email protected]](C4=CC=CC=C4)([H])CC3)=O)=NC2=O

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

Description

APJ receptor agonist 5 (compound 3) is a potent and orally active agonist of apelin receptor (APJ) with an EC50 of 0.4 nM. APJ receptor agonist 5 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 5 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 leads to improved cardiac function and can be used for researching the HF disease.

! For research use only. Not intended for any clinical use.