Angiotensin II, (human)
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Angiotensin II, (human)

Cat. No: CDIA-0063
CAS. No.: 4474-91-3
Synonyms: Angiotensin II; Ang II; DRVYIHPF
Size: 1 mg
Price: Inquiry
Product Details
Formula C50H71N13O12
Molecular Weight 1046.18
Appearance Solid
Purity 99.45%
Sequence Asp-Arg-Val-Tyr-Ile-His-Pro-Phe
Sequence Shortening DRVYIHPF
Storage & Handling
Shipping Room temperature.
Storage Sealed storage, away from moisture and light, under nitrogen *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Storage Powder -80 °C/2 years, -20 °C/1 year

Description

Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway.

! For research use only. Not intended for any clinical use.