Angiotensin (1-7) (acetate)
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Angiotensin (1-7) (acetate)

Cat. No: CDIA-0299
CAS. No.: 2855063-75-9
Synonyms: Ang-(1-7) (acetate)
Size: 1 mg
Price: Inquiry
Product Details
Formula C43H66N12O13
Molecular Weight 959.06
Appearance Solid
Purity 98.91%
Sequence Asp-Arg-Val-Tyr-Ile-His-Pro
Sequence Shortening DRVYIHP
Storage & Handling
Shipping Room temperature.
Storage Sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)
Storage Powder -80 °C/2 years, -20 °C/1 year

Description

Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium.

! For research use only. Not intended for any clinical use.