AACOCF3

Cat. No: CDIA-0451

CAS. No.: 149301-79-1

Synonyms: Arachidonyl trifluoromethyl ketone

Size: 5 mg

Price: Inquiry

Product Details
Formula	C21H31F3O
Molecular Weight	356.47
Appearance	Liquid
Purity	≥98.0%
Smiles String	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(C(F)(F)F)=O

Storage & Handling
Shipping	Room temperature.
Storage	Solution, -20 °C, 2 years

Description

AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. AACOCF3 has the potential for the research of cardiovascular disease.

! For research use only. Not intended for any clinical use.