A 71915
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A 71915

Cat. No: CDIA-1564
CAS. No.: 132956-87-7
Size: 50 mg
Price: Inquiry
Product Details
Formula C69H116N26O15S2
Molecular Weight 1613.95
Appearance Solid
Purity 99.29%
Sequence Arg-Cys-Cha-Gly-Gly-Arg-Ile-Asp-Arg-Ile-D-tic-Arg-Cys-NH2 (Disulfide bridge: Cys2-Cys13)
Sequence Shortening {RC-Cha}-GGRIDRI-{D-Tic-RC}-NH2 (Disulfide bridge: Cys2-Cys13)
Storage & Handling
Shipping Room temperature.
Storage Sealed storage, away from moisture and light, under nitrogen *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Storage Powder -80 °C/2 years, -20 °C/1 year

Description

A 71915 is a highly potent and competitive natriuretic peptide receptor A (ANP, NPRA) antagonist (pKi= 9.18). A 71915 displaces [125I]ANP dose dependently, with a Ki of 0.65 nM. A71915( pA2= 9.48) against rat ANP-induced cGMP production in NB-OK-1 cells.

! For research use only. Not intended for any clinical use.

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