(3S, 5R)-Rosuvastatin
Online Inquiry
* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

(3S, 5R)-Rosuvastatin

Cat. No: CDIA-1991
CAS. No.: 1242184-42-4
Size: 500 μg
Price: Inquiry
Product Details
Formula C22H28FN3O6S
Molecular Weight 481.54
Smiles String O=C(O)C[[email protected]@H](O)C[[email protected]@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2
Storage & Handling
Shipping Room temperature.
Storage Please refer to the instruction manual.

Description

(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

! For research use only. Not intended for any clinical use.